Recombinant human LAMTOR4 protein

LAMTOR4 is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Recombinant human LAMTOR4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Ragulator complex protein LAMTOR4, C7orf59

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

13.1 kDa (122aa) confirmed by MALDI-TOF

Additionnal Information

LAMTOR4, Ragulator complex protein LAMTOR4, C7orf59, ATGP2791-10 µg, ATGP2791-20 µg, ATGP2791-50 µg, ATGP2791-100 µg, ATGP2791-250 µg, ATGP2791-500 µg, ATGP2791-1 mg, ATGP2791-10, ATGP2791-20, ATGP2791-50, ATGP2791-100, ATGP2791-250, ATGP2791-500, ATGP2791-1