Recombinant human ASB13 protein

ASB13 is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and Ccomplex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants, both protein-coding and not protein-coding, have been described for this gene. Recombinant human ASB13 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Ankyrin repeat and SOCS box containing 13, FLJ13134, MGC19879

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

32.4 kDa (301aa)

Additionnal Information

ASB13, ankyrin repeat and SOCS box containing 13, FLJ13134, MGC19879, ATGP2783-10 µg, ATGP2783-20 µg, ATGP2783-50 µg, ATGP2783-100 µg, ATGP2783-250 µg, ATGP2783-500 µg, ATGP2783-1 mg, ATGP2783-10, ATGP2783-20, ATGP2783-50, ATGP2783-100, ATGP2783-250, ATGP2783-500, ATGP2783-1

References & Citations

Kohroki, J, et al. (2005) FEBS Lett. 579 (30), 6796-6802; ; Kile, B.T., et al. (2002) Trends Biochem. Sci. 27 (5), 235-241

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol

Scientific Category

Other

NCBI Accession Number

NP_078977

Uniprot Accession Number

Q8WXK3

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMEPRAAD GCFLGDVGFW VERTPVHEAA QRGESLQLQQ LIESGACVNQ VTVDSITPLH AASLQGQARC VQLLLAAGAQ VDARNIDGST PLCDACASGS IECVKLLLSY GAKVNPPLYT ASPLHEACMS GSSECVRLLI DVGANLEAHD CHFGTPLHVA CAREHLDCVK VLLNAGANVN AAKLHETALH HAAKVKNVDL IEMLIEFGGN IYARDNRGKK PSDYTWSSSA PAKCFEYYEK TPLTLSQLCR VNLRKATGVR GLEKIAKLNI PPRLIDYLSY N