Recombinant human Kallikrein 11/KLK11 protein
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in multiple transcript variants encoding distinct isoforms which are differentially expressed. Recombinant human KLK11 protein was expressed in E. coli.
Product Specifications
Product Name Alternative
Kallikrein-11 isoform 2, Kallikrein related peptidase 11, KLK11, hK11, Hippostasin, Serine protease 20, Trypsin-like protease, PRSS20, TLSP
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
24.8 kDa (226aa)
Additionnal Information
References & Citations
Patsis C, Yiotakis I, et al. (2012) Clin Biochem. ; ;45 (9) :623-30. doi: 10.1016.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea
Scientific Category
Signal Transduction
NCBI Accession Number
NP_659196
Uniprot Accession Number
Q9UBX7
Species
Human
AA Sequence
Frequently Asked Questions
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