Recombinant human Kallikrein 11/KLK11 protein

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in multiple transcript variants encoding distinct isoforms which are differentially expressed. Recombinant human KLK11 protein was expressed in E. coli.

Product Specifications

Product Name Alternative

Kallikrein-11 isoform 2, Kallikrein related peptidase 11, KLK11, hK11, Hippostasin, Serine protease 20, Trypsin-like protease, PRSS20, TLSP

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

24.8 kDa (226aa)

Additionnal Information

Kallikrein11, Kallikrein 11, PRSS20, TLSP, ATGP2773-10 µg, ATGP2773-20 µg, ATGP2773-50 µg, ATGP2773-100 µg, ATGP2773-250 µg, ATGP2773-500 µg, ATGP2773-1 mg, ATGP2773-10, ATGP2773-20, ATGP2773-50, ATGP2773-100, ATGP2773-250, ATGP2773-500, ATGP2773-1

References & Citations

Patsis C, Yiotakis I, et al. (2012) Clin Biochem. ; ;45 (9) :623-30. doi: 10.1016.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea

Scientific Category

Signal Transduction

NCBI Accession Number

NP_659196

Uniprot Accession Number

Q9UBX7

Species

Human

AA Sequence

MIIKGFECKP HSQPWQAALF EKTRLLCGAT LIAPRWLLTA AHCLKPRYIV HLGQHNLQKE EGCEQTRTAT ESFPHPGFNN SLPNKDHRND IMLVKMASPV SITWAVRPLT LSSRCVTAGT SCLISGWGST SSPQLRLPHT LRCANITIIE HQKCENAYPG NITDTMVCAS VQEGGKDSCQ GDSGGPLVCN QSLQGIISWG QDPCAITRKP GVYTKVCKYV DWIQET