Recombinant human CMG-2 protein

ANTXR2 is called anthrax toxin receptor 2 because it allows the toxin that causes anthrax to attach to cells and trigger disease. This protein is involved in the formation of tiny blood vessels (capillaries) . It is also important for maintaining the structure of basement membranes, which are thin, sheet-like structures that separate and support cells in many tissues. Recombinant human ANTXR2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Anthrax toxin receptor 2, CMG-2, m CMG2, HFS, ISH, JHF

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

33.0 kDa (307aa) confirmed by MALDI-TOF

Additionnal Information

CMG2, ATGP2762-10 µg, ATGP2762-20 µg, ATGP2762-50 µg, ATGP2762-100 µg, ATGP2762-250 µg, ATGP2762-500 µg, ATGP2762-1 mg, ATGP2762-10, ATGP2762-20, ATGP2762-50, ATGP2762-100, ATGP2762-250, ATGP2762-500, ATGP2762-1

References & Citations

Scobie HM, A. et al. (2003) Proc Natl Acad Sci u S A. 100 : 5170-5174.; ; Abrami L. et al. (2003) J. Cell Biol. 160 : 321-328;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 1mM DTT, 0.1M NaCl

Scientific Category

Neuroscience

NCBI Accession Number

NP_001139266

Uniprot Accession Number

P58335

Species

Human

AA Sequence

QEQPSCR RAFDLYFVLD KSGSVANNWI EIYNFVQQLA ERFVSPEMRL SFIVFSSQAT IILPLTGDRG KISKGLEDLK RVSPVGETYI HEGLKLANEQ IQKAGGLKTS SIIIALTDGK LDGLVPSYAE KEAKISRSLG ASVYCVGVLD FEQAQLERIA DSKEQVFPVK GGFQALKGII NSILAQSCTE ILELQPSSVC VGEEFQIVLS GRGFMLGSRN GSVLCTYTVN ETYTTSVKPV SVQLNSMLCP APILNKAGET LDVSVSFNGG KSVISGSLIV TATECSN