Recombinant human THAP11 protein

THAP domain-containing protein 11, also known as THAP11, is a member of the thanatos-associated protein family. Localizing to the nucleus and cytoplasm, THAP11 may act as a transcriptional repressor, playing a role in embryogenesis and pluripotency of embryonic stem cells by recruiting epigenetic modifiers. THAP11 interacts with HCF1 via a coiled coil domain. Recombinant human THAP11 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

THAP domain-containing protein 11, CTG-B43a, CTG-B45d, HRIHFB2206, RONIN

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 80% by SDS-PAGE

Molecular Weight

36.8 kDa (337aa)

Additionnal Information

THAP11, THAP domain-containing protein 11, CTG-B43a, CTG-B45d, HRIHFB2206, RONIN, ATGP2742-10 µg, ATGP2742-20 µg, ATGP2742-50 µg, ATGP2742-100 µg, ATGP2742-250 µg, ATGP2742-500 µg, ATGP2742-1 mg, ATGP2742-10, ATGP2742-20, ATGP2742-50, ATGP2742-100, ATGP2742-250, ATGP2742-500, ATGP2742-1

References & Citations

Pandey N., et al. (2004) J Hum Genet. 49: 596-602.; ; Liew C K., et al. (2007) J Mol Biol. 366: 382-390.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_065190

Uniprot Accession Number

Q96EK4

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMPGFTCC VPGCYNNSHR DKALHFYTFP KDAELRRLWL KNVSRAGVSG CFSTFQPTTG HRLCSVHFQG GRKTYTVRVP TIFPLRGVNE RKVARRPAGA AAARRRQQQQ QQQQQQQQQQ QQQQQQQQQQ QQQQQSSPSA STAQTAQLQP NLVSASAAVL LTLQATVDSS QAPGSVQPAP ITPTGEDVKP IDLTVQVEFA AAEGAAAAAA ASELQAATAG LEAAECPMGP QLVVVGEEGF PDTGSDHSYS LSSGTTEEEL LRKLNEQRDI LALMEVKMKE MKGSIRHLRL TEAKLREELR EKDRLLAMAV IRKKHGM