Recombinant human THAP11 protein
THAP domain-containing protein 11, also known as THAP11, is a member of the thanatos-associated protein family. Localizing to the nucleus and cytoplasm, THAP11 may act as a transcriptional repressor, playing a role in embryogenesis and pluripotency of embryonic stem cells by recruiting epigenetic modifiers. THAP11 interacts with HCF1 via a coiled coil domain. Recombinant human THAP11 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
THAP domain-containing protein 11, CTG-B43a, CTG-B45d, HRIHFB2206, RONIN
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 80% by SDS-PAGE
Molecular Weight
36.8 kDa (337aa)
Additionnal Information
References & Citations
Pandey N., et al. (2004) J Hum Genet. 49: 596-602.; ; Liew C K., et al. (2007) J Mol Biol. 366: 382-390.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_065190
Uniprot Accession Number
Q96EK4
Species
Human
AA Sequence
Frequently Asked Questions
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