Recombinant human GCHFR protein

GTP cyclohydrolase I feedback regulatory protein (GCHFR) binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide. Recombinant human GCHFR protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

GTP cyclohydrolase I feedback regulatory protein, GFRP, HsT16933, P35

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

12.1 kDa (107aa) confirmed by MALDI-TOF

Additionnal Information

GCHFR, GTP cyclohydrolase I feedback regulatory protein, GFRP, HsT16933, P35, ATGP2738-10 µg, ATGP2738-20 µg, ATGP2738-50 µg, ATGP2738-100 µg, ATGP2738-250 µg, ATGP2738-500 µg, ATGP2738-1 mg, ATGP2738-10, ATGP2738-20, ATGP2738-50, ATGP2738-100, ATGP2738-250, ATGP2738-500, ATGP2738-1