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Recombinant human LANCL1 protein

LANCL1 is a loosely associated peripheral membrane protein related to the LanC family of bacterial membrane-associated proteins involved in the biosynthesis of antimicrobial peptides. This protein may play a role as a peptide-modifying enzyme component in eukaryotic cells. Previously considered a member of the G-protein-coupled receptor superfamily, this protein is now in the LanC family. Multiple alternatively spliced variants, encoding the same protein, have been identified. Recombinant human LANCL1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

LanC-like protein 1, GPR69A, p40

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

47.7 kDa (422aa) confirmed by MALDI-TOF

Additionnal Information

LANCL1, lanC-like protein 1, GPR69A, p40, ATGP2736-10 µg, ATGP2736-20 µg, ATGP2736-50 µg, ATGP2736-100 µg, ATGP2736-250 µg, ATGP2736-500 µg, ATGP2736-1 mg, ATGP2736-10, ATGP2736-20, ATGP2736-50, ATGP2736-100, ATGP2736-250, ATGP2736-500, ATGP2736-1

References & Citations

Zhang W., et al (2009) . Genes Dev. 23:1387-1392; ; Blisnick T., et al (2005) . Mol. Biochem. Parasitol. 141:39-47

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 7.5) containing 0.15M NaCl, 20% glycerol, 1mM DTT

Scientific Category

Cardiovascular

NCBI Accession Number

NP_006046

Uniprot Accession Number

O43813

Species

Human

AA Sequence

MAQRAFP NPYADYNKSL AEGYFDAAGR LTPEFSQRLT NKIRELLQQM ERGLKSADPR DGTGYTGWAG IAVLYLHLYD VFGDPAYLQL AHGYVKQSLN CLTKRSITFL CGDAGPLAVA AVLYHKMNNE KQAEDCITRL IHLNKIDPHA PNEMLYGRIG YIYALLFVNK NFGVEKIPQS HIQQICETIL TSGENLARKR NFTAKSPLMY EWYQEYYVGA AHGLAGIYYY LMQPSLQVSQ GKLHSLVKPS VDYVCQLKFP SGNYPPCIGD NRDLLVHWCH GAPGVIYMLI QAYKVFREEK YLCDAYQCAD VIWQYGLLKK GYGLCHGSAG NAYAFLTLYN LTQDMKYLYR ACKFAEWCLE YGEHGCRTPD TPFSLFEGMA GTIYFLADLL VPTKARFPAF EL

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