Recombinant human SAMSN1 protein

SAMSN1, also known as HACS1, is a member of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains. This protein is up-regulated by IL-4 in activated B cells and strongly expressed in dendritic cells. It may have a function analogous to other adaptor proteins that link signaling molecules in signal transduction cascades. Recombinant human SAMSN1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

SAM domain-containing protein SAMSN-1, HACS1, NASH1, SASH2, SH3D6B, SLy2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 80% by SDS-PAGE

Molecular Weight

44.1 kDa (396aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Additionnal Information

SAMSN1, SAM domain-containing protein SAMSN-1, HACS1, NASH1, SASH2, SH3D6B, SLy2, ATGP2725-10 µg, ATGP2725-20 µg, ATGP2725-50 µg, ATGP2725-100 µg, ATGP2725-250 µg, ATGP2725-500 µg, ATGP2725-1 mg, ATGP2725-10, ATGP2725-20, ATGP2725-50, ATGP2725-100, ATGP2725-250, ATGP2725-500, ATGP2725-1

References & Citations

Zhu YX. et al. (2004) J Exp Med. 200:737-747; ; Wang D. et al. (2010) FASEB J. 24:947-956.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 30% glycerol 0.1M NaCl,1mM DTT

Scientific Category

Stem Cell

NCBI Accession Number

NP_071419

Uniprot Accession Number

Q9NSI8

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMLKRKPS NVSEKEKHQK PKRSSSFGNF DRFRNNSLSK PDDSTEAHEG DPTNGSGEQS KTSNNGGGLG KKMRAISWTM KKKVGKKYIK ALSEEKDEED GENAHPYRNS DPVIGTHTEK VSLKASDSMD SLYSGQSSSS GITSCSDGTS NRDSFRLDDD GPYSGPFCGR ARVHTDFTPS PYDTDSLKIK KGDIIDIICK TPMGMWTGML NNKVGNFKFI YVDVISEEEA APKKIKANRR SNSKKSKTLQ EFLERIHLQE YTSTLLLNGY ETLEDLKDIK ESHLIELNIE NPDDRRRLLS AAENFLEEEI IQEQENEPEP LSLSSDISLN KSQLDDCPRD SGCYISSGNS DNGKEDLESE NLSDMVHKII ITEPSD