Recombinant human COA4 protein

Cytochrome c oxidase assembly factor 4 homolog, mitochondrial, also known as COA4, is the last enzyme of the mitochondrial respiratory chain, is a very complicated process and requires the assistance of a large number of accessory factors. It is essential for oxidative phosphorylation and comprises multiple complexes, including cytochrome c oxidase, assembled in macromolecular supercomplexes. Defects in COX4 assembly alter cellular respiration and produce severe human encephalomyopathies. Recombinant human COA4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Cytochrome c oxidase assembly factor 4 homolog mitochondrial, Cytochrome c oxidase assembly factor 4 homolog, mitochondrial, CHCHD8, CMC3, E2IG2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

12.5 kDa (110aa) confirmed by MALDI-TOF

Additionnal Information

COA4, Cytochrome c oxidase assembly factor 4 homolog mitochondrial, Cytochrome c oxidase assembly factor 4 homolog, mitochondrial, CHCHD8, CMC3, E2IG2, ATGP2716-10 µg, ATGP2716-20 µg, ATGP2716-50 µg, ATGP2716-100 µg, ATGP2716-250 µg, ATGP2716-500 µg, ATGP2716-1 mg, ATGP2716-10, ATGP2716-20, ATGP2716-50, ATGP2716-100, ATGP2716-250, ATGP2716-500, ATGP2716-1