Recombinant human PKNOX1 protein
Hmeobox protein PKNOX1 is a DNA-binding protein that forms stable complexes with PBX proteins which synergize with AP-1 binding factors to augment transcription of the urokinase gene. Also referred to as uEF3, PRP-1 or p64, PKNOX1 appears to be a general DNA-binding factor involved in modulating the transcriptional activity of AP-1 containing promoters. Recombinant human PKNOX1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Hmeobox protein PKNOX1, pkonx1c, PREP1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 80% by SDS-PAGE
Molecular Weight
49.7 kDa (456aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Nourse J., et al. (1990) Cell. 60: 535-545.; ; Monica K P., et al. (1991) Mol Cell Biol. 11: 6149-6157.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_004562
Uniprot Accession Number
P55347
Species
Human
AA Sequence
Frequently Asked Questions
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