Recombinant human PIM2 protein

Serine/threonine-protein kinase pim-2, also known as PIM2, is a serine/threonine protein kinase in the CAMK family. PIM2 is expressed in many tissues, with high levels in spleen, thymus, testis, small intestine, and colon. It is implicated in tumor phenotypes and may be involved in the formation and preservation of Long-Term Potentiation (LTP), a profuse, activity-dependent enhancement of synaptic efficacy that is implicated in long-term memory. Recombinant human PIM2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Serine/threonine-protein kinase pim-2, pim-2 oncogene

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

36.6 kDa (334aa) confirmed by MALDI-TOF

Additionnal Information

PIM2, Serine/threonine-protein kinase pim-2, pim-2 oncogene, ATGP2699-10 µg, ATGP2699-20 µg, ATGP2699-50 µg, ATGP2699-100 µg, ATGP2699-250 µg, ATGP2699-500 µg, ATGP2699-1 mg, ATGP2699-10, ATGP2699-20, ATGP2699-50, ATGP2699-100, ATGP2699-250, ATGP2699-500, ATGP2699-1

References & Citations

Hammerman P S., et al. (2005) Blood. 105: 4477-4483.; ; Fox C J., et al. (2003) Genes Dev. 17: 1841-1854.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol

Scientific Category

Signal Transduction

NCBI Accession Number

NP_006866

Uniprot Accession Number

Q9P1W9

Species

Human

AA Sequence

MLTKPLQ GPPAPPGTPT PPPGGKDREA FEAEYRLGPL LGKGGFGTVF AGHRLTDRLQ VAIKVIPRNR VLGWSPLSDS VTCPLEVALL WKVGAGGGHP GVIRLLDWFE TQEGFMLVLE RPLPAQDLFD YITEKGPLGE GPSRCFFGQV VAAIQHCHSR GVVHRDIKDE NILIDLRRGC AKLIDFGSGA LLHDEPYTDF DGTRVYSPPE WISRHQYHAL PATVWSLGIL LYDMVCGDIP FERDQEILEA ELHFPAHVSP DCCALIRRCL APKPSSRPSL EEILLDPWMQ TPAEDVPLNP SKGGPAPLAW SLLP