Recombinant human PIM2 protein
Serine/threonine-protein kinase pim-2, also known as PIM2, is a serine/threonine protein kinase in the CAMK family. PIM2 is expressed in many tissues, with high levels in spleen, thymus, testis, small intestine, and colon. It is implicated in tumor phenotypes and may be involved in the formation and preservation of Long-Term Potentiation (LTP), a profuse, activity-dependent enhancement of synaptic efficacy that is implicated in long-term memory. Recombinant human PIM2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Serine/threonine-protein kinase pim-2, pim-2 oncogene
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
36.6 kDa (334aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Hammerman P S., et al. (2005) Blood. 105: 4477-4483.; ; Fox C J., et al. (2003) Genes Dev. 17: 1841-1854.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol
Scientific Category
Signal Transduction
NCBI Accession Number
NP_006866
Uniprot Accession Number
Q9P1W9
Species
Human
AA Sequence
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