Recombinant human Perilipin-2 protein

PLIN2 belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Recombinant human PLIN2, fused to T7-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Adipose differentiation-related protein, adipose differentiation-related protein, ADFP, ADRP, MGC10598

Expression System

E.coli

Antigen Species

Human

Tag

T7-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

49.3 kDa (451aa)

Additionnal Information

Perilipin2, adipose differentiation-related protein, adipose differentiation-related protein, ADFP, ADRP, MGC10598, ATGP2694-10 µg, ATGP2694-20 µg, ATGP2694-50 µg, ATGP2694-100 µg, ATGP2694-250 µg, ATGP2694-500 µg, ATGP2694-1 mg, ATGP2694-10, ATGP2694-20, ATGP2694-50, ATGP2694-100, ATGP2694-250, ATGP2694-500, ATGP2694-1

References & Citations

Shaw, C.S., et al. (2012) Am. J. Physiol. Endocrinol. Metab. 303 (9), E1158-E1165 ; ; Peters, S.J., et al. (2012) Appl Physiol Nutr Metab 37 (4), 724-735;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol

Scientific Category

Cardiovascular

NCBI Accession Number

NP_001113.2

Uniprot Accession Number

Q99541

Species

Human

AA Sequence

MASVAV DPQPSVVTRV VNLPLVSSTY DLMSSAYLST KDQYPYLKSV CEMAENGVKT ITSVAMTSAL PIIQKLEPQI AVANTYACKG LDRIEERLPI LNQPSTQIVA NAKGAVTGAK DAVTTTVTGA KDSVASTITG VMDKTKGAVT GSVEKTKSVV SGSINTVLGS RMMQLVSSGV ENALTKSELL VEQYLPLTEE ELEKEAKKVE GFDLVQKPSY YVRLGSLSTK LHSRAYQQAL SRVKEAKQKS QQTISQLHST VHLIEFARKN VYSANQKIQD AQDKLYLSWV EWKRSIGYDD TDESHCAEHI ESRTLAIARN LTQQLQTTCH TLLSNIQGVP QNIQDQAKHM GVMAGDIYSV FRNAASFKEV SDSLLTSSKG QLQKMKESLD DVMDYLVNNT PLNWLVGPFY PQLTESQNAQ DQGAEMDKSS QETQRSEHKT H