Recombinant human TSFM protein
TSFM is a mitochondrial translation elongation factor. It is an enzyme that catalyzes the exchange of guanine nucleotides on the translation elongation factor Tu during the elongation step of mitchondrial protein translation. Mutations in TSFM are associated with combined oxidative phosphorylation deficiency-3 syndrome. Alternate splicing results in multiple transcript variants. Recombinant human TSFM protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Ts translation elongation factor mitochondrial, Ts translation elongation factor, mitochondrial, COXPD3, EF-TS, EF-Tsmt
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
32.9 kDa (302aa)
Additionnal Information
References & Citations
Xin H. et al. (1995) J Biol Chem. 270:17243-17249.; ; Smeitink JA. et al. (2006) Am. J. Hum. Genet. 79:869-877.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_005717.2
Uniprot Accession Number
P43897
Species
Human
AA Sequence
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Atonal Homolog 1 (ATOH1) BioAssayTM ELISA Kit (Human) discontinued
Atonal Homolog 1 (ATOH1) BioAssayTM ELISA Kit (Human) discontinued
