Recombinant human MKPX/DUSP22 protein
DuSP22 belongs to the protein-tyrosine phosphatase family and contains 1 tyrosine-protein phosphatase domain. This protein activates the Jnk signaling pathway and dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) . Recombinant human DuSP22 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
23.3 kDa (207aa)
Additionnal Information
References & Citations
Shen Y., et al. (2001) Proc. Natl. Acad. Sci. u.S.A. 98:13613-13618; ; Schwertassek u., et al. (2010) FEBS J. 277:2463-2473;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Cell Cycle
NCBI Accession Number
NP_064570
Uniprot Accession Number
Q9NRW4
Species
Human
AA Sequence
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