Recombinant human HOXA9 protein
HOXA9 belongs to the Abd-B homeobox family. This protein is a transcription factor with a central role in both haemopoiesis and leukaemia. High levels of HOXA9 expression in haemopoietic cells is a characteristic feature of acute myeloid leukaemia (AML), and may be sufficient to cause this disease. Overexpression of Hoxa 9 markedly expands hematopoietic stem cells. Recombinant human HOXA9 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Homeobox protein Hox-A9, ABD-B, HOX1, HOX1.7, HOX1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
32.6 kDa (295aa)
Additionnal Information
References & Citations
Bandyopadhyay S., et al. (2012) Mol. Cell. Biol. 32:1202-1213; ; Patel C.V., et al. (1999) J. Biol. Chem. 274:1415-1422;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Stem Cell
NCBI Accession Number
NP_689952
Uniprot Accession Number
P31269
Species
Human
AA Sequence
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