Recombinant human HOXA9 protein

HOXA9 belongs to the Abd-B homeobox family. This protein is a transcription factor with a central role in both haemopoiesis and leukaemia. High levels of HOXA9 expression in haemopoietic cells is a characteristic feature of acute myeloid leukaemia (AML), and may be sufficient to cause this disease. Overexpression of Hoxa 9 markedly expands hematopoietic stem cells. Recombinant human HOXA9 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Homeobox protein Hox-A9, ABD-B, HOX1, HOX1.7, HOX1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

32.6 kDa (295aa)

Additionnal Information

HOXA9, Homeobox protein Hox-A9, ABD-B, HOX1, HOX1.7, HOX1, ATGP2667-10 µg, ATGP2667-20 µg, ATGP2667-50 µg, ATGP2667-100 µg, ATGP2667-250 µg, ATGP2667-500 µg, ATGP2667-1 mg, ATGP2667-10, ATGP2667-20, ATGP2667-50, ATGP2667-100, ATGP2667-250, ATGP2667-500, ATGP2667-1

References & Citations

Bandyopadhyay S., et al. (2012) Mol. Cell. Biol. 32:1202-1213; ; Patel C.V., et al. (1999) J. Biol. Chem. 274:1415-1422;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Stem Cell

NCBI Accession Number

NP_689952

Uniprot Accession Number

P31269

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMATTGAL GNYYVDSFLL GADAADELSV GRYAPGTLGQ PPRQAATLAE HPDFSPCSFQ SKATVFGASW NPVHAAGANA VPAAVYHHHH HHPYVHPQAP VAAAAPDGRY MRSWLEPTPG ALSFAGLPSS RPYGIKPEPL SARRGDCPTL DTHTLSLTDY ACGSPPVDRE KQPSEGAFSE NNAENESGGD KPPIDPNNPA ANWLHARSTR KKRCPYTKHQ TLELEKEFLF NMYLTRDRRY EVARLLNLTE RQVKIWFQNR RMKMKKINKD RAKDE