Recombinant human GNB1 protein
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. GNB1 encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Recombinant human GNB1 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Guanine nucleotide-binding protein G (I) /G (S) /G (T) subunit beta-1, guanine nucleotide binding protein (G protein), beta polypeptide 1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
39.8 kDa (363aa)
Additionnal Information
References & Citations
Bhatnagar, A, et al. (2013) PLoS ONE 8 (1), E52689 ; ; Lim, Y.P., et al. (2012) BMC Gastroenterol 12, 167;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol
Scientific Category
Signal Transduction
NCBI Accession Number
NP_002065
Uniprot Accession Number
P62873
Species
Human
AA Sequence
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