Recombinant human Kallikrein 10/KLK10 protein

KLK10, also known as Kallikrein-10, is one of the fifteen kallikrein subfamily members. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. It is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Recombinant human KLK10 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

PRSSL1, Protease serine-like 1, Normal epithelial cell-specific 1, NES1, KLK10, Kallikrein-10, Kallikrein related peptidase 10

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

29.1 kDa (266aa)

Additionnal Information

PRSSL1, Protease serine-like 1, Normal epithelial cell-specific 1, NES1, KLK10, Kallikrein-10, Kallikrein related peptidase 10, ATGP2664-10 µg, ATGP2664-20 µg, ATGP2664-50 µg, ATGP2664-100 µg, ATGP2664-250 µg, ATGP2664-500 µg, ATGP2664-1 mg, ATGP2664-010, ATGP2664-020, ATGP2664-050, ATGP2664-100, ATGP2664-250, ATGP2664-500, ATGP2664-01M

References & Citations

Liu XL. et al. (1996) Cancer Res. 56:3371-3379.; ; Zhang Y. et al. (2006) Biol. Chem. 387:715-721.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Scientific Category

Cytoskeleton

NCBI Accession Number

NP_001070968

Uniprot Accession Number

O43240

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSALLPQND TRLDPEAYGS PCARGSQPWQ VSLFNGLSFH CAGVLVDQSW VLTAAHCGNK PLWARVGDDH LLLLQGEQLR RTTRSVVHPK YHQGSGPILP RRTDEHDLML LKLARPVVLG PRVRALQLPY RCAQPGDQCQ VAGWGTTAAR RVKYNKGLTC SSITILSPKE CEVFYPGVVT NNMICAGLDR GQDPCQSDSG GPLVCDETLQ GILSWGVYPC GSAQHPAVYT QICKYMSWIN KVIRSN