Recombinant human Kallikrein 10/KLK10 protein
KLK10, also known as Kallikrein-10, is one of the fifteen kallikrein subfamily members. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. It is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Recombinant human KLK10 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
PRSSL1, Protease serine-like 1, Normal epithelial cell-specific 1, NES1, KLK10, Kallikrein-10, Kallikrein related peptidase 10
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
29.1 kDa (266aa)
Additionnal Information
References & Citations
Liu XL. et al. (1996) Cancer Res. 56:3371-3379.; ; Zhang Y. et al. (2006) Biol. Chem. 387:715-721.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea
Scientific Category
Cytoskeleton
NCBI Accession Number
NP_001070968
Uniprot Accession Number
O43240
Species
Human
AA Sequence
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