Recombinant human RSU1 protein

RSU1 is a protein that is involved in the ras signal transduction pathway, growth inhibition, and nerve-growth factor induced differentiation processes, as determined in mouse and human cell line studies. In mouse, RSU1 was initially isolated based on its ability to inhibit v-Ras transformation. Multiple alternatively spliced transcript variants for this gene have been reported; one of these variants was found only in glioma tumors. Recombinant human RSU1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Ras suppressor protein 1, RSP-1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

33.9 kDa (300aa)

Additionnal Information

RSu1, Ras suppressor protein 1, RSP-1, ATGP2662-10 µg, ATGP2662-20 µg, ATGP2662-50 µg, ATGP2662-100 µg, ATGP2662-250 µg, ATGP2662-500 µg, ATGP2662-1 mg, ATGP2662-10, ATGP2662-20, ATGP2662-50, ATGP2662-100, ATGP2662-250, ATGP2662-500, ATGP2662-1

References & Citations

Gevaert K., et al. (2003) Nat. Biotechnol. 21:566-569; ; Aboulaich N., et al. (2004) Biochem. J. 383:237-248;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Signal Transduction

NCBI Accession Number

NP_036557

Uniprot Accession Number

Q15404

Species

Human

AA Sequence

MSKSLKK LVEESREKNQ PEVDMSDRGI SNMLDVNGLF TLSHITQLVL SHNKLTMVPP NIAELKNLEV LNFFNNQIEE LPTQISSLQK LKHLNLGMNR LNTLPRGFGS LPALEVLDLT YNNLSENSLP GNFFYLTTLR ALYLSDNDFE ILPPDIGKLT KLQILSLRDN DLISLPKEIG ELTQLKELHI QGNRLTVLPP ELGNLDLTGQ KQVFKAENNP WVTPIADQFQ LGVSHVFEYI RSETYKYLYG RHMQANPEPP KKNNDKSKKI SRKPLAAKNR