Recombinant human CPEB1 protein
CPEB1 is a member of the cytoplasmic polyadenylation element (CPE) binding protein family. This highly conserved protein binds to a specific RNA sequence called the CPE found in the 3' uTR of some mRNAs. Similar proteins in Xenopus and mouse function to induce cytoplasmic polyadenylation of dormant mRNAs with short polyA tails, resulting in their translation. Members of this protein family regulate translation of cyclin B1 during embryonic cell divisions. Recombinant human CPEB1 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Cytoplasmic polyadenylation element bindi ng protein 1, CEBP, CPE-BP1, CPEB
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
64.5 kDa (584aa)
Additionnal Information
References & Citations
Sasayama T., et al. (2005) Genes Cells. 10:627-638; ; Wilczynska A., et al. (2005) J. Cell Sci. 118:981-992;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_085097
Uniprot Accession Number
Q9BZB8
Species
Human
AA Sequence
Frequently Asked Questions
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