Recombinant human CPEB1 protein

CPEB1 is a member of the cytoplasmic polyadenylation element (CPE) binding protein family. This highly conserved protein binds to a specific RNA sequence called the CPE found in the 3' uTR of some mRNAs. Similar proteins in Xenopus and mouse function to induce cytoplasmic polyadenylation of dormant mRNAs with short polyA tails, resulting in their translation. Members of this protein family regulate translation of cyclin B1 during embryonic cell divisions. Recombinant human CPEB1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Cytoplasmic polyadenylation element bindi ng protein 1, CEBP, CPE-BP1, CPEB

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

64.5 kDa (584aa)

Additionnal Information

CPEB1, Cytoplasmic polyadenylation element bindi ng protein 1, CEBP, CPE-BP1, CPEB, ATGP2659-10 µg, ATGP2659-20 µg, ATGP2659-50 µg, ATGP2659-100 µg, ATGP2659-250 µg, ATGP2659-500 µg, ATGP2659-1 mg, ATGP2659-10, ATGP2659-20, ATGP2659-50, ATGP2659-100, ATGP2659-250, ATGP2659-500, ATGP2659-1

References & Citations

Sasayama T., et al. (2005) Genes Cells. 10:627-638; ; Wilczynska A., et al. (2005) J. Cell Sci. 118:981-992;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_085097

Uniprot Accession Number

Q9BZB8

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMAFPLEE EAGRIKDCWD NQEAPALSTC SNANIFRRIN AILDNSLDFS RVCTTPINRG IHDHLPDFQD SEETVTSRML FPTSAQESSR GLPDANDLCL GLQSLSLTGW DRPWSTQDSD SSAQSSTHSV LSMLHNPLGN VLGKPPLSFL PLDPLGSDLV DKFPAPSVRG SRLDTRPILD SRSSSPSDSD TSGFSSGSDH LSDLISSLRI SPPLPFLSLS GGGPRDPLKM GVGSRMDQEQ AALAAVTPSP TSASKRWPGA SVWPSWDLLE APKDPFSIER EARLHRQAAA VNEATCTWSG QLPPRNYKNP IYSCKVFLGG VPWDITEAGL VNTFRVFGSL SVEWPGKDGK HPRCPPKGYV YLVFELEKSV RSLLQACSHD PLSPDGLSEY YFKMSSRRMR CKEVQVIPWV LADSNFVRSP SQRLDPSRTV FVGALHGMLN AEALAAILND LFGGVVYAGI DTDKHKYPIG SGRVTFNNQR SYLKAVSAAF VEIKTTKFTK KVQIDPYLED SLCHICSSQP GPFFCRDQVC FKYFCRSCWH WRHSMEGLRH HSPLMRNQKN RDSS