Recombinant human PF4V1/CXCL4L1 protein

PF4V1 belongs to the intercrine alpha (chemokine CxC) family. It is a inhibitor of angiogenesis and inhibitor of endothelial cell chemotaxis (in vitro) . Binding to heparin is much weaker than in the close homolog PF4/CXCL4. Recombinant human PF4V1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Platelet factor 4 variant 1, Platelet factor 4 variant, C-X-C motif chemokine 4 variant, CXCL4L1, PF4alt, PF4var1, SCYB4V1, CXCL4V1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

10.6 kDa (97aa) confirmed by MALDI-TOF

Additionnal Information

PF4V1, ATGP2655-10 µg, ATGP2655-20 µg, ATGP2655-50 µg, ATGP2655-100 µg, ATGP2655-250 µg, ATGP2655-500 µg, ATGP2655-1 mg, ATGP2655-10, ATGP2655-20, ATGP2655-50, ATGP2655-100, ATGP2655-250, ATGP2655-500, ATGP2655-1

References & Citations

Green CJ, Charles RS, et al. (1989) . Mol Cell Biol. 9 (4) :1445-51.; ; Eisman R, Surrey S, et al. (1990) . Blood. 76 (2) :336-44.; ; Struyf S, Burdick MD, et al. (2004) . Circ Res. 95 (9) :855-7.; ; Kuo JH, Chen YP, et al. (2013) . J Biol Chem. 288 (19) :13522-33.;