Recombinant human TSSK6 protein
TSSK6, also known as testis-specific serine/threonine-protein kinase 6, is a member of the CAMK Ser/Thr protein kinase family. This protein contains one protein kinase domain. It is highly expressed in the testis and lowly expressed in the colon, prostate, thymus, small intestine, and peripheral blood leukocytes. It interacts with the heatshock proteins HSPA8, HSPCB, and HAPA1A; these interactions appear to be required for TSSK6 kinase activity. It plays a role in DNA condensation during postmeiotic chromatin remodeling. Otherwise, TSSK6 is required for sperm production and function. Recombinant human TSSK6 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Testis-specific serine kinase 6, CT72, FKSG82, SSTK, TSSK4
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 80% by SDS-PAGE
Molecular Weight
32.7 kDa (296aa)
Additionnal Information
References & Citations
Su D. et al. (2010) Asian J Androl. 12:234-239.; ; Sosnik J et al. (2009) J Cell Sci. 122:2741-2749.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea
Scientific Category
Cell Cycle
NCBI Accession Number
NP_114426.1
Uniprot Accession Number
Q9BXA6
Species
Human
AA Sequence
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