Recombinant human TSSK6 protein

TSSK6, also known as testis-specific serine/threonine-protein kinase 6, is a member of the CAMK Ser/Thr protein kinase family. This protein contains one protein kinase domain. It is highly expressed in the testis and lowly expressed in the colon, prostate, thymus, small intestine, and peripheral blood leukocytes. It interacts with the heatshock proteins HSPA8, HSPCB, and HAPA1A; these interactions appear to be required for TSSK6 kinase activity. It plays a role in DNA condensation during postmeiotic chromatin remodeling. Otherwise, TSSK6 is required for sperm production and function. Recombinant human TSSK6 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Testis-specific serine kinase 6, CT72, FKSG82, SSTK, TSSK4

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 80% by SDS-PAGE

Molecular Weight

32.7 kDa (296aa)

Additionnal Information

TSSK6, Testis-specific serine kinase 6, CT72, FKSG82, SSTK, TSSK4, ATGP2635-10 µg, ATGP2635-20 µg, ATGP2635-50 µg, ATGP2635-100 µg, ATGP2635-250 µg, ATGP2635-500 µg, ATGP2635-1 mg, ATGP2635-10, ATGP2635-20, ATGP2635-50, ATGP2635-100, ATGP2635-250, ATGP2635-500, ATGP2635-1

References & Citations

Su D. et al. (2010) Asian J Androl. 12:234-239.; ; Sosnik J et al. (2009) J Cell Sci. 122:2741-2749.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Scientific Category

Cell Cycle

NCBI Accession Number

NP_114426.1

Uniprot Accession Number

Q9BXA6

Species

Human

AA Sequence

MSGDKLL SELGYKLGRT IGEGSYSKVK VATSKKYKGT VAIKVVDRRR APPDFVNKFL PRELSILRGV RHPHIVHVFE FIEVCNGKLY IVMEAAATDL LQAVQRNGRI PGVQARDLFA QIAGAVRYLH DHHLVHRDLK CENVLLSPDE RRVKLTDFGF GRQAHGYPDL STTYCGSAAY ASPEVLLGIP YDPKKYDVWS MGVVLYVMVT GCMPFDDSDI AGLPRRQKRG VLYPEGLELS ERCKALIAEL LQFSPSARPS AGQVARNCWL RAGDSG