Recombinant human MZB1 protein
Marginal zone B- and B1-cell-specific protein, also known as MZB1, acts as a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. This protein may have a role in the onset of insulin resistance. Recombinant human MZB1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Marginal zone B- and B1-cell-specific protein, PACAP, MEDA7
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
12.9 kDa (120aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Bonfoco E., et al. (2001) J. Biol. Chem. 276:29242-29250; ; Zhang H., et al. (2011) Diabetologia. 54:2368-2380;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Scientific Category
Apoptosis
NCBI Accession Number
AAH09931
Uniprot Accession Number
Q8WU39
Species
Human
AA Sequence
MPAELWL TSYGVREVDQ VKRLTGPGLS EGPEPSISVM VTGGPWPTRL SRTCLHYLGE FGEDQIYEAH QQGRGALEAL LCGGPQGACS EKVSATREEL
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