Recombinant human ZNHIT1 protein

ZNHIT1 belongs to the ZNHIT1 family and contains 1 HIT-type zinc finger. The protein is induced by DNA damage and seems to play role in p53-mediated apoptosis induction. ZNHIT1 interacts with MAPK11 and MAPK14 and is component of the chromatin-remodeling SRCAP complex composed of at least SRCAP, DMAP1, RuVBL1, RuVBL2, ACTL6A, YEATS4, ACTR6 and ZNHIT1. Recombinant human ZNHIT1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Zinc finger HIT domain-containing protein 1, Zinc finger, HIT-type containing 1, CG1I, ZNFN4A1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

19.9 kDa (177aa)

Additionnal Information

ZNHIT1, Zinc finger HIT domain-containing protein 1, Zinc finger, HIT-type containing 1, CG1I, ZNFN4A1, ATGP2627-10 µg, ATGP2627-20 µg, ATGP2627-50 µg, ATGP2627-100 µg, ATGP2627-250 µg, ATGP2627-500 µg, ATGP2627-1 mg, ATGP2627-10, ATGP2627-20, ATGP2627-50, ATGP2627-100, ATGP2627-250, ATGP2627-500, ATGP2627-1

References & Citations

Cuadrado A., et al. (2007) EMBO J. 26:2115-2126

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea

Scientific Category

Apoptosis

NCBI Accession Number

NP_006340

Uniprot Accession Number

O43257

Species

Human

AA Sequence

MVEKKTS VRSQDPGQRR VLDRAARQRR INRQLEALEN DNFQDDPHAG LPQLGKRLPQ FDDDADTGKK KKKTRGDHFK LRFRKNFQAL LEEQNLSVAE GPNYLTACAG PPSRPQRPFC AVCGFPSPYT CVSCGARYCT VRCLGTHQET RCLKWTV