Recombinant human SIKE1 protein

SIKE interacts with IKK-epsilon and TBK1 and acts as a suppressor of TLR3 and virus-triggered interferon activation pathways. Recombinant human SIKE1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Suppressor of IKBKE 1 isoform 2, suppressor of IKBKE 1 isoform 2, RP5-1000E10.4, SIKE

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

26.1 kDa (230aa) confirmed by MALDI-TOF

Additionnal Information

SIKE1, suppressor of IKBKE 1 isoform 2, suppressor of IKBKE 1 isoform 2, RP5-1000E10.4, SIKE, ATGP2618-10 µg, ATGP2618-20 µg, ATGP2618-50 µg, ATGP2618-100 µg, ATGP2618-250 µg, ATGP2618-500 µg, ATGP2618-1 mg, ATGP2618-10, ATGP2618-20, ATGP2618-50, ATGP2618-100, ATGP2618-250, ATGP2618-500, ATGP2618-1

References & Citations

Huang J., et al (2005) . EMBO J. 24:4018-4028; ; The MGC Project Team., et al (2004) . Genome Res. 14:2121-2127;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT

Scientific Category

Immunology

NCBI Accession Number

NP_079349

Uniprot Accession Number

Q9BRV8

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMSCTIEK ILTDAKTLLE RLREHDAAAE SLVDQSAALH RRVAAMREAG TALPDQYQED ASDMKDMSKY KPHILLSQEN TQIRDLQQEN RELWISLEEH QDALELIMSK YRKQMLQLMV AKKAVDAEPV LKAHQSHSAE IESQIDRICE MGEVMRKAVQ VDDDQFCKIQ EKLAQLELEN KELRELLSIS SESLQARKEN SMDTASQAIK