Recombinant human Glutathione S-transferase mu 1/GSTM1 protein

Glutathione S-transferase mu 1 isoform 2, also known as GSTM1, is a glutathione S-transferase that belongs to the mu class. GSTs (glutathione S-transferase) are differentially expressed in lung, liver and kidney tissue and, notably, three isoforms (GSTA1-1, GSTA1-4 and GSTM1) localize to the mitochondria in addition to the cytoplasm. The GSTM1 of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. Recombinant human GSTM1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Mu-1, Mu, H-B, GTM1, GTH4, GSTM1b-1b, GSTM1a-1a, GSTM1-1, GST1, Glutathione S-transferase mu 1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

23.6 kDa (203aa)

Additionnal Information

MU-1, MU1, MU, H-B, GTM1, GTM 1, GTH4, GTH 4, GSTM1b-1b, GSTM1b 1b, GSTM1a-1a, GSTM1a 1a, GSTM1-1, GSTM1 1, GSTM1, GSTM 1, GST1, GST 1, Glutathione S-transferase Mu 1 isoform 1, Glutathione S-transferase Mu 1, ATGP2611-10 µg, ATGP2611-20 µg, ATGP2611-50 µg, ATGP2611-100 µg, ATGP2611-250 µg, ATGP2611-500 µg, ATGP2611-1 mg, ATGP2611-010, ATGP2611-020, ATGP2611-050, ATGP2611-100, ATGP2611-250, ATGP2611-500, ATGP2611-01M

References & Citations

Bartley P A., et al. (2003) Oncogene. 22:7570-7575.; ; Moretti M., et al. (2007) BMC Public Health. 7:270.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Metabolism

NCBI Accession Number

NP_666533

Uniprot Accession Number

P09488

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH RSMPMILGYW DIRGLAHAIR LLLEYTDSSY EEKKYTMGDA PDYDRSQWLN EKFKLGLDFP NLPYLIDGAH KITQSNAILC YIARKHNLCG ETEEEKIRVD ILENQTMDNH MQLGMICYNP EFEKLKPKYL EELPEKLKLY SEFLGKRPWF AGNKGLEKIS AYMKSSRFLP RPVFSKMAVW GNK