Recombinant human Casein kinase 1 alpha/CSNK1A1 protein

Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. CSNK1A1 participates in Wnt signaling and phosphorylates CTNNB1 at 'Ser-45'. It may play a role in segregating chromosomes during mitosis. Recombinant human CSNK1a1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Casein kinase 1 alpha 1, CK1, CK1a, CK1alpha, CKIa, CKIalpha, Clock regulator kinase

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 80% by SDS-PAGE

Molecular Weight

41 kDa (357aa)

Additionnal Information

CSNK1A1, Casein kinase 1 alpha 1, Casein kinase 1, alpha 1, CK1, HLCDGP1, PRO2975, ATGP2610-10 µg, ATGP2610-20 µg, ATGP2610-50 µg, ATGP2610-100 µg, ATGP2610-250 µg, ATGP2610-500 µg, ATGP2610-1 mg, ATGP2610-10, ATGP2610-20, ATGP2610-50, ATGP2610-100, ATGP2610-250, ATGP2610-500, ATGP2610-1

References & Citations

Dubois T, Kerai P, et al. (2001) . J Biol Chem. 276 (22) :18757-64.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Stem cell

NCBI Accession Number

NP_001883

Uniprot Accession Number

P48729

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MASSSGSKAE FIVGGKYKLV RKIGSGSFGD IYLAINITNG EEVAVKLESQ KARHPQLLYE SKLYKILQGG VGIPHIRWYG QEKDYNVLVM DLLGPSLEDL FNFCSRRFTM KTVLMLADQM ISRIEYVHTK NFIHRDIKPD NFLMGIGRHC NKLFLIDFGL AKKYRDNRTR QHIPYREDKN LTGTARYASI NAHLGIEQSR RDDMESLGYV LMYFNRTSLP WQGLKAATKK QKYEKISEKK MSTPVEVLCK GFPAEFAMYL NYCRGLRFEE APDYMYLRQL FRILFRTLNH QYDYTFDWTM LKQKAAQQAA SSSGQGQQAQ TPTGKQTDKT KSNMKGF