Recombinant human sFRP-2/SFRP2 protein

SFRP2, as known as secreted frizzled-related protein 2, is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. This protein acts as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer. Recombinant human SFRP2 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Secreted frizzled-related protein 2, FRP-2, sFRP-2, Secreted apoptosis-related protein 1, SARP-1, SDF-5

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

33.8 kDa (297aa)

Additionnal Information

SFRP2, Secreted frizzled-related protein 2, Secreted frizzled-related protein 2, FRP-2, SARP1, SDF-5, ATGP2606-10 µg, ATGP2606-20 µg, ATGP2606-50 µg, ATGP2606-100 µg, ATGP2606-250 µg, ATGP2606-500 µg, ATGP2606-1 mg, ATGP2606-10, ATGP2606-20, ATGP2606-50, ATGP2606-100, ATGP2606-250, ATGP2606-500, ATGP2606-1

References & Citations

Melkonyan HS. et al. (1998) Proc Natl Acad Sci u S A. 94:13636-13641.; ; Lescher B. et al. (1999) Dev. Dyn. 213:440-451.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Scientific Category

Stem cell

NCBI Accession Number

NP_003004

Uniprot Accession Number

Q96HF1

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSARGLFLF GQPDFSYKRS NCKPIPVNLQ LCHGIEYQNM RLPNLLGHET MKEVLEQAGA WIPLVMKQCH PDTKKFLCSL FAPVCLDDLD ETIQPCHSLC VQVKDRCAPV MSAFGFPWPD MLECDRFPQD NDLCIPLASS DHLLPATEEA PKVCEACKNK NDDDNDIMET LCKNDFALKI KVKEITYINR DTKIILETKS KTIYKLNGVS ERDLKKSVLW LKDSLQCTCE EMNDINAPYL VMGQKQGGEL VITSVKRWQK GQREFKRISR SIRKLQC