Recombinant human Angiogenin protein
ANG, as known as Angiogenin, belongs to RNase A family. This protein is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. Recombinant human ANG protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Angiogenin ribonuclease RNase A family 5, Angiogenin, ribonuclease, RNase A family, 5, ALS9, HEL168, MGC22466, MGC71966, RNASE4, RNASE5
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
16.4 kDa (144aa)
Additionnal Information
References & Citations
Kuwahara A. et al. (2012) Biosci Trends. 6:229-633.; ; Neubauer-Geryk J. et al. (2012) Microvasc Res. 84:387-389.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea
Scientific Category
Metabolism
NCBI Accession Number
NP_001136
Uniprot Accession Number
P03950
Species
Human
AA Sequence
QDNSRYTHF LTQHYDAKPQ GRDDRYCESI MRRRGLTSPC KDINTFIHGN KRSIKAICEN KNGNPHRENL RISKSSFQVT TCKLHGGSPW PPCQYRATAG FRNVVVACEN GLPVHLDQSI FRRP
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