Recombinant human HPR protein
HPR, also known as Haptoglobin-related protein, is a primate-specific plasma protein associated with apolipoprotein L-I (apoL-I) -containing high-density lipoprotein (HDL) particles shown to be a part of the innate immune defense. HPR-bound hemoglobin might contribute to the biologic activity of the circulating apoL-I/Hpr-containing HDL particles. Recombinant human HPR protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Haptoglobin-related protein, A-259H10.2, HP
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
39.3 kDa (352aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Nielsen MJ. et al. (2008) Blood. 108:2846-2849.; ; Imrie HJ. et al. (2012) PLoS One. 7:e49816;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH8.5) containing 20% glycerol, 1mM DTT, 0.15M NaCl
Scientific Category
Cancer
NCBI Accession Number
NP_066275
Uniprot Accession Number
P00739
Species
Human
AA Sequence
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