Recombinant human KRT17 protein

KRT17, as known as keratin17, is a type I cytokeratin. It is found in nail beds, hair follicles, sebaceous glands, and other epidermal appendages. Mutations in KRT17 lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. Recombinant human KRT17 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Keratin type I cytoskeletal 17, Keratin, type I cytoskeletal 17, K17, PC, PC2, PCHC1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

50.5 kDa (455aa)

Additionnal Information

KRT17, Keratin type I cytoskeletal 17, Keratin, type I cytoskeletal 17, K17, PC, PC2, PCHC1, ATGP2580-10 µg, ATGP2580-20 µg, ATGP2580-50 µg, ATGP2580-100 µg, ATGP2580-250 µg, ATGP2580-500 µg, ATGP2580-1 mg, ATGP2580-10, ATGP2580-20, ATGP2580-50, ATGP2580-100, ATGP2580-250, ATGP2580-500, ATGP2580-1

References & Citations

McLean WH. et al. (1995) Nat Genet. 9:273-278.; ; Troyanovsky SM. et al. (1993) Eur J Cell Biol. 59: 127-137.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Scientific Category

Signal Transduction

NCBI Accession Number

NP_000413

Uniprot Accession Number

Q04695

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMTTSIRQ FTSSSSIKGS SGLGGGSSRT SCRLSGGLGA GSCRLGSAGG LGSTLGGSSY SSCYSFGSGG GYGSSFGGVD GLLAGGEKAT MQNLNDRLAS YLDKVRALEE ANTELEVKIR DWYQRQAPGP ARDYSQYYRT IEELQNKILT ATVDNANILL QIDNARLAAD DFRTKFETEQ ALRLSVEADI NGLRRVLDEL TLARADLEMQ IENLKEELAY LKKNHEEEMN ALRGQVGGEI NVEMDAAPGV DLSRILNEMR DQYEKMAEKN RKDAEDWFFS KTEELNREVA TNSELVQSGK SEISELRRTM QALEIELQSQ LSMKASLEGN LAETENRYCV QLSQIQGLIG SVEEQLAQLR CEMEQQNQEY KILLDVKTRL EQEIATYRRL LEGEDAHLTQ YKKEPVTTRQ VRTIVEEVQD GKVISSREQV HQTTR