Recombinant human Clusterin/CLU protein
CLu, also known as clusterin, is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants. Recombinant human CLu protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Clusterin, CLI, AAG4, APOJ, KuB1, SGP2, SGP-2, SP-40, TRPM2, TRPM-2, MGC24903
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
54.1 kDa (463aa)
Additionnal Information
References & Citations
Leskov K.S., et al. (2003) J. Biol. Chem. 278:11590-11600; ; Takahashi M., et al. (2004) Oncogene. 23:9289-9294;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Scientific Category
Metabolism
NCBI Accession Number
NP_001822
Uniprot Accession Number
P10909
Species
Human
AA Sequence
Frequently Asked Questions
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