Recombinant human Calreticulin-2 protein

Calreticulin 3, also known as CALR3, is a member of the calreticulin (CRT) family. It is calcium-binding chaperones that are localized to the endoplasmic reticulum or sarcoplasmic reticulum in eukaryotes. CALR3 assists in the calreticulin/calnexin cycle, where it is involved in protein-folding, oligomeric assembly and quality control in the ER. With specific expression in testis, CALR3 has been implicated as a cancer-testis antigen due to its frequent expression in various cancers. Recombinant human CALR3 protein was expressed in E. coli.

Product Specifications

Product Name Alternative

Calreticulin 3, CRT2, FLJ25355, MGC26577

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

43 kDa (366aa)

Additionnal Information

Calreticulin2, Calreticulin 3, CRT2, FLJ25355, MGC26577, ATGP2573-10 µg, ATGP2573-20 µg, ATGP2573-50 µg, ATGP2573-100 µg, ATGP2573-250 µg, ATGP2573-500 µg, ATGP2573-1 mg, ATGP2573-10, ATGP2573-20, ATGP2573-50, ATGP2573-100, ATGP2573-250, ATGP2573-500, ATGP2573-1

References & Citations

Persson S., et al. (2002) Gene. 297: 151-158.; ; Michalak M., et al. (1998) Biochem Cell Biol. 76: 779-785.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Signal Transduction

NCBI Accession Number

NP_659483

Uniprot Accession Number

Q96L12

Species

Human

AA Sequence

MTVYFQEEFL DGEHWRNRWL QSTNDSRFGH FRLSSGKFYG HKEKDKGLQT TQNGRFYAIS ARFKPFSNKG KTLVIQYTVK HEQKMDCGGG YIKVFPADID QKNLNGKSQY YIMFGPDICG FDIKKVHVIL HFKNKYHENK KLIRCKVDGF THLYTLILRP DLSYDVKIDG QSIESGSIEY DWNLTSLKKE TSPAESKDWE QTKDNKAQDW EKHFLDASTS KQSDWNGDLD GDWPAPMLQK PPYQDGLKPE GIHKDVWLHR KMKNTDYLTQ YDLSEFENIG AIGLELWQVR SGTIFDNFLI TDDEEYADNF GKATWGETKG PEREMDAIQA KEEMKKAREE EEEELLSGKI NRHEHYFNQF HRRNEL