Recombinant Human EpCAM/TROP1 Protein (ECD, His & AVI Tag, Biotinylated)

<strong>Recombinant Human EpCAM/TROP1 Protein (ECD, His &amp; AVI Tag, Biotinylated)</strong>_x000D_ <strong>Catalog number:</strong> B2018956_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 30.7 kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −20°C_x000D_ <strong>Keywords:</strong> 17-1A Protein, Human; 323/A3 Protein, Human; Ber-Ep4 Protein, Human; BerEp4 Protein, Human; CD326 Protein, Human; CO-17A Protein, Human; DIAR5 Protein, Human; EGP-2 Protein, Human; EGP314 Protein, Human; EGP34 Protein, Human; EGP40 Protein, Human; Ep-CAM Protein, Human; EPCAM Protein, Human; ESA Protein, Human; GA733-2 Protein, Human; HEA125 Protein, Human; HNPCC8 Protein, Human; KS1/4 Protein, Human; KSA Protein, Human; Ly74 Protein, Human; LYNCH8 Protein, Human; M1S2 Protein, Human; M4S1 Protein, Human; MH99 Protein, Human; MIC18 Protein, Human; MK-1 Protein, Human; MOC-31 Protein, Human; MOC31 Protein, Human; TACST-1 Protein, Human; TACSTD1 Protein, Human; TROP1 Protein, Human_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Alberti S, Nutini M, Herzenberg LA. DNA methylation prevents the amplification of TROP1, a tumor-associated cell surface antigen gene Proc Natl Acad Sci U S A. 1994 Jun 21;91(13):5833-7._x000D_ 2: Nasr AF, Nutini M, Palombo B, Guerra E, Alberti S. Mutations of TP53 induce loss of DNA methylation and amplification of the TROP1 gene Oncogene. 2003 Mar 20;22(11):1668-77._x000D_ 3: Lee BC, Jung MY, Cho D, O-Sullivan I, Cohen EP, Kim TS. Immunity to Trop-1, a newly identified breast cancer antigen, inhibits the growth of breast cancer in mice Vaccine. 2010 Nov 16;28(49):7757-63._x000D_ 4: Rashid MH. Full-length recombinant antibodies from Escherichia coli: production, characterization, effector function (Fc) engineering, and clinical evaluation MAbs. 2022 Jan-Dec;14(1):2111748._x000D_ 5: Sankpal NV, Mayfield JD, Willman MW, Fleming TP, Gillanders WE. Activator protein 1 (AP-1) contributes to EpCAM-dependent breast cancer invasion Breast Cancer Res. 2011;13(6):R124._x000D_ 6: Barzaman K, Samadi M, Moradi-Kalbolandi S, Majidzadeh-A K, Salehi M, Jalili N, Jazayeri MH, Khorammi S, Darvishi B, Siavashi V, Shekarabi M, Farahmand L. Development of a recombinant anti-VEGFR2-EPCAM bispecific antibody to improve antiangiogenic efficiency Exp Cell Res. 2021 Aug 15;405(2):112685._x000D_ 7: Yoshida H, Shiokawa M, Kuwada T, Muramoto Y, Ota S, Nishikawa Y, Maeda H, Kakiuchi N, Okamoto K, Yamazaki H, Yokode M, Nakamura T, Matsumoto S, Hirano T, Okada H, Marui S, Sogabe Y, Matsumori T, Mima A, Uza N, Eso Y, Takai A, Takahashi K, Ueda Y, Kodama Y, Chiba T, Seno H. Anti-integrin αvβ6 autoantibodies in patients with primary sclerosing cholangitis J Gastroenterol. 2023 Aug;58(8):778-789._x000D_ 8: Lv M, Qiu F, Li T, Sun Y, Zhang C, Zhu P, Qi X, Wan J, Yang K, Zhang K. Construction, expression, and characterization of a recombinant immunotoxin targeting EpCAM Mediators Inflamm. 2015;2015:460264._x000D_ 9: Hristodorov D, Amoury M, Mladenov R, Niesen J, Arens K, Berges N, Hein L, Di Fiore S, Pham AT, Huhn M, Helfrich W, Fischer R, Thepen T, Barth S. EpCAM-selective elimination of carcinoma cells by a novel MAP-based cytolytic fusion protein Mol Cancer Ther. 2014 Sep;13(9):2194-202._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/32979162">10: Babaee N, Talebkhan Garoosi Y, Karimipoor M, Davami F, Bayat E, Safarpour H, Mahboudi F, Barkhordari F. DARPin Ec1-LMWP protein scaffold in targeted delivery of siRNA molecules through EpCAM cancer stem cell marker Mol Biol Rep. 2020 Oct;47(10):7323-7331. </a>_x000D_ _x000D_ <strong>Products Related to Recombinant Human EpCAM/TROP1 Protein (ECD, His &amp; AVI Tag, Biotinylated) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>