Recombinant human Epoxide Hydrolase 1/EPHX1 protein
Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Recombinant human EPHX1 protein, fused to T7-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Epoxide hydrolase 1, Epoxide hydrolase 1 microsomal (xenobiotic), MEH, EPHX, EPOX
Expression System
E.coli
Antigen Species
Human
Tag
T7-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
52.2 kDa (451aa)
Additionnal Information
References & Citations
Nguyen HL, et al. RNA, (2013) . PMID 23564882.; ; Wang S, et al. Tumour Biol, (2013) . PMID 23378225.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea
Scientific Category
Metabolism
NCBI Accession Number
NP_000111
Uniprot Accession Number
P07099
Species
Human
AA Sequence
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