Recombinant human Neurexophilin-1/NXPH-1 protein

NXPH1 is a member of the neurexophilin family and encodes a secreted protein with a variable N-terminal domain, a highly conserved, N-glycosylated central domain, a short linker region, and a cysteine-rich C-terminal domain. This protein forms a very tight complex with alpha neurexins, a group of proteins that promote adhesion between dendrites and axons. Recombinant human NXPH1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Neurexophilin-1 precursor, neurexophilin-1 precursor, Nbla00697, NPH1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

31kDa (273aa)

Additionnal Information

Neurexophilin1, NXPH1, neurexophilin-1 precursor, neurexophilin-1 precursor, Nbla00697, NPH1, ATGP2539-10 µg, ATGP2539-20 µg, ATGP2539-50 µg, ATGP2539-100 µg, ATGP2539-250 µg, ATGP2539-500 µg, ATGP2539-1 mg, ATGP2539-10, ATGP2539-20, ATGP2539-50, ATGP2539-100, ATGP2539-250, ATGP2539-500, ATGP2539-1

References & Citations

Faryna, M., et al. (2012) FASEB J. 26 (12), 4937-4950; ; Frazier-Wood, A.C., et al. (2012) Pharmacogenet. Genomics 22 (10), 750-757;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol

Scientific Category

Neuroscience

NCBI Accession Number

NP_689958

Uniprot Accession Number

P58417

Species

Human

AA Sequence

ANLTNGG KSELLKSGSS KSTLKHIWTE SSKDLSISRL LSQTFRGKEN DTDLDLRYDT PEPYSEQDLW DWLRNSTDLQ EPRPRAKRRP IVKTGKFKKM FGWGDFHSNI KTVKLNLLIT GKIVDHGNGT FSVYFRHNST GQGNVSVSLV PPTKIVEFDL AQQTVIDAKD SKSFNCRIEY EKVDKATKNT LCNYDPSKTC YQEQTQSHVS WLCSKPFKVI CIYISFYSTD YKLVQKVCPD YNYHSDTPYF PSG