Recombinant human p130Cas protein

BCAR1, or CAS, is an Src family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion. Recombinant human BCAR1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Breast cancer anti-estrogen resistance 1, CAS, CAS1, CASS1, CRKAS, P130Cas

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

43.9 kDa (407aa)

Additionnal Information

P130Cas, breast cancer anti-estrogen resistance 1, CAS, CAS1, CASS1, CRKAS, P130Cas, ATGP2538-10 µg, ATGP2538-20 µg, ATGP2538-50 µg, ATGP2538-100 µg, ATGP2538-250 µg, ATGP2538-500 µg, ATGP2538-1 mg, ATGP2538-10, ATGP2538-20, ATGP2538-50, ATGP2538-100, ATGP2538-250, ATGP2538-500, ATGP2538-1

References & Citations

Konstantinovsky, S, et al. (2012) Clin. Exp. Metastasis 29 (6), 527-540; ; Huang, W., et al. (2012) PLoS ONE 7 (4), E36124;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol

Scientific Category

Cancer

NCBI Accession Number

NP_055382

Uniprot Accession Number

P56945

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSRLQQGVS ATVAHLLDLA GSAGATGSWR SPSEPQEPLV QDLQAAVAAV QSAVHELLEF ARSAVGNAAH TSDRALHAKL SRQLQKMEDV HQTLVAHGQA LDAGRGGSGA TLEDLDRLVA CSRAVPEDAK QLASFLHGNA SLLFRRTKAT APGPEGGGTL HPNPTDKTSS IQSRPLPSPP KFTSQDSPDG QYENSEGGWM EDYDYVHLQG KEEFEKTQKE LLEKGSITRQ GKSQLELQQL KQFERLEQEV SRPIDHDLAN WTPAQPLAPG RTGGLGPSDR QLLLFYLEQC EANLTTLTNA VDAFFTAVAT NQPPKIFVAH SKFVILSAHK LVFIGDTLSR QAKAADVRSQ VTHYSNLLCD LLRGIVATTK AAALQYPSPS AAQDMVE