Recombinant human MMP-10 protein
MMP10 protein of the matrix metalloproteinase (MMP) family is involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. MMP10 is part of a cluster of MMP genes which localize to chromosome 11q22. 3. Recombinant human MMP10 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Stromelysin-2 preproprotein, SL-2, STMY2
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
45.4 kDa (401aa)
Additionnal Information
References & Citations
Wojciechowski, R., et al. (2013) Ophthalmology 120 (2), 298-305 ; ; Sze, K.M., et al. (2013) Hepatology 57 (1), 131-139;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol
Scientific Category
Cancer
NCBI Accession Number
NP_002416
Uniprot Accession Number
P09238
Species
Human
AA Sequence
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