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Recombinant human MT3 protein

Metallothionein 3, also known as MT3, binds heavy metals. This protein contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. This protein inhibits survival and neurite formation of cortical neurons in vitro. Recombinant human MT3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Metallothionein 3, Metallothionein 3, GIF, GIFB, GRIF, ZnMT3

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by BCA assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

9.3 kDa (91aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Additionnal Information

MT3, Metallothionein 3, Metallothionein 3, GIF, GIFB, GRIF, ZnMT3, ATGP2535-10 µg, ATGP2535-20 µg, ATGP2535-50 µg, ATGP2535-100 µg, ATGP2535-250 µg, ATGP2535-500 µg, ATGP2535-1 mg, ATGP2535-10, ATGP2535-20, ATGP2535-50, ATGP2535-100, ATGP2535-250, ATGP2535-500, ATGP2535-1

References & Citations

Uchida Y., et al. (1991) Neuron. 7:337-347; ; Palmiter R.D., et al. (1992) Proc. Natl. Acad. Sci. u.S.A. 89:6333-6337;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol

Scientific Category

Metabolism

NCBI Accession Number

NP_005945.1

Uniprot Accession Number

P25713

Species

Human

AA Sequence

MDPETCP CPSGGSCTCA DSCKCEGCKC TSCKKSCCSC CPAECEKCAK DCVCKGGEAA EAEAEKCSCC Q

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