Recombinant human RLBP1 protein
RLBP1 is a 36-kD water-soluble protein which carries 11-cis-retinaldehyde or 11-cis-retinal as physiologic ligands. It may be a functional component of the visual cycle. Mutations of this gene have been associated with severe rod-cone dystrophy, Bothnia dystrophy (nonsyndromic autosomal recessive retinitis pigmentosa) and retinitis punctata albescens. Recombinant human RLBP1 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Retinaldehyde-binding protein 1, CRALBP
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
38.9 kDa (340aa)
Additionnal Information
References & Citations
Nojima, K., et al. (2012) Ophthalmic Genet. 33 (2), 83-88; ; Neutzner, R.V., et al. (2011) Ophthalmologe 108 (11), 1045-1049;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol
Scientific Category
Neuroscience
NCBI Accession Number
NP_000317
Uniprot Accession Number
P12271
Species
Human
AA Sequence
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