Recombinant human RLBP1 protein

RLBP1 is a 36-kD water-soluble protein which carries 11-cis-retinaldehyde or 11-cis-retinal as physiologic ligands. It may be a functional component of the visual cycle. Mutations of this gene have been associated with severe rod-cone dystrophy, Bothnia dystrophy (nonsyndromic autosomal recessive retinitis pigmentosa) and retinitis punctata albescens. Recombinant human RLBP1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Retinaldehyde-binding protein 1, CRALBP

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

38.9 kDa (340aa)

Additionnal Information

RLBP1, retinaldehyde-binding protein 1, CRALBP, ATGP2522-10 µg, ATGP2522-20 µg, ATGP2522-50 µg, ATGP2522-100 µg, ATGP2522-250 µg, ATGP2522-500 µg, ATGP2522-1 mg, ATGP2522-10, ATGP2522-20, ATGP2522-50, ATGP2522-100, ATGP2522-250, ATGP2522-500, ATGP2522-1

References & Citations

Nojima, K., et al. (2012) Ophthalmic Genet. 33 (2), 83-88; ; Neutzner, R.V., et al. (2011) Ophthalmologe 108 (11), 1045-1049;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol

Scientific Category

Neuroscience

NCBI Accession Number

NP_000317

Uniprot Accession Number

P12271

Species

Human

AA Sequence

MSEGVGT FRMVPEEEQE LRAQLEQLTT KDHGPVFGPC SQLPRHTLQK AKDELNEREE TREEAVRELQ EMVQAQAASG EELAVAVAER VQEKDSGFFL RFIRARKFNV GRAYELLRGY VNFRLQYPEL FDSLSPEAVR CTIEAGYPGV LSSRDKYGRV VMLFNIENWQ SQEITFDEIL QAYCFILEKL LENEETQING FCIIENFKGF TMQQAASLRT SDLRKMVDML QDSFPARFKA IHFIHQPWYF TTTYNVVKPF LKSKLLERVF VHGDDLSGFY QEIDENILPS DFGGTLPKYD GKAVAEQLFG PQAQAENTAF