Recombinant human protocadherin/PCDHGC4 protein

PCDHGL4 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Recombinant human PCDHGL4 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Protocadherin gamma-C4 isoform 2 precursor, PCDH-GAMMA-C4

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

74.3 kDa (684aa)

Additionnal Information

PCDHGC4, protocadherin gamma-C4 isoform 2 precursor, PCDH-GAMMA-C4, ATGP2521-10 µg, ATGP2521-20 µg, ATGP2521-50 µg, ATGP2521-100 µg, ATGP2521-250 µg, ATGP2521-500 µg, ATGP2521-1 mg, ATGP2521-10, ATGP2521-20, ATGP2521-50, ATGP2521-100, ATGP2521-250, ATGP2521-500, ATGP2521-1

References & Citations

Wu, Q., et al. (2001) Genome Res. 11 (3), 389-404; ; Nollet, F., et al. (2000) J. Mol. Biol. 299 (3), 551-572;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol

Scientific Category

Signal Transduction

NCBI Accession Number

NP_115782

Uniprot Accession Number

Q9Y5F7

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MQIRYPVPEE SQEGTFVGNV AQDFLLDTDS LSARRLQVAG EVNQRHFRVD LDSGALLIKN PIDREALCGL SASCIVPLEF VTEGPLEMYR AEVEIVDVND HAPRFPRQQL DLEIGEAAPP GQRFPLEKAQ DADVGSNSIS SYRLSSNEHF ALDVKKRSDG SLVPELLLEK PLDREKQSDY RLVLTAVDGG NPPRSGTAEL RVSVLDVNDN APAFQQSSYR ISVLESAPAG MVLIQLNASD PDLGPSGNVT FYFSGHTPDR VRNLFSLHPT TGKLTLLGPL DFESENYYEF DVRARDGGSP AMEQHCSLRV DLLDVNDNAP YITVTSELGT LPESAEPGTV VALISVQDPD SGSNGDVSLR IPDHLPFALK SAFRNQFSLV TAGPLDREAK SSYDIMVTAS DAGNPPLSTH RTIFLNISDV NDNPPSFFQR SHEVFVPENN RPGDLLCSLA ASDPDSGLNA LISYSLLEPR NRDVSASSFI SLNPQTGAVH ATRSFDYEQT QTLQFEVQAR DRGNPPLSST VTVRLFVLDL NDNAPAVLRP RARPGSLCPQ ALPPSVGAGH LITKVTAVDL DSGYNAWVSY QLLEAPDPSL FAVSRYAGEV RTAVPIPADL PPQKLVIVVK DSGSPPLSTS VTLLVSLEED THPVVPDLRE SSAPREGESR LTLY