Recombinant human GNG4 protein
Guanine nucleotide-binding protein G (I) /G (S) /G (O) subunit gamma-4 precursor, also known as GNG4, is members of a multigene family and are implicated in determining the specificity of receptor-G protein interaction. In mammals, G protein alpha, beta and gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively. GNG4 is becoming increasingly clear that different G protein complexes expressed in different tissues carry structurally distinct members of the gamma as well as the alpha and beta subunits and that preferential association between members of subunit families increase G protein functional diversity. Recombinant human GNG4 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
10.4 kDa (95aa)
Additionnal Information
References & Citations
Kalyanaraman S., et al. (1998) Genomics. 49 (1) : 147-51.; ; Simon N I., et al. (1991) Science. 252: 802-808.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Metabolism
NCBI Accession Number
NP_001092192
Uniprot Accession Number
P50150
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMKEGMSN NSTTSISQAR KAVEQLKMEA CMDRVKVSQA AADLLAYCEA HVREDPLIIP VPASENPFRE KKFFC
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