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Recombinant human Resistin/RETN protein

RETN belongs to the family defined by the mouse resistin-like genes. The characteristic feature of this family is the C-terminal stretch of 10 cys residues with identical spacing. The mouse homolog of this protein is secreted by adipocytes, and may be the hormone potentially linking obesity to type II diabetes. Alternatively spliced transcript variants encoding the same protein have been found for this gene. Recombinant human RETN protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Adipose tissue-specific secretory factor, ADSF, C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein A12-alpha-like 2, Cysteine-rich secreted protein FIZZ3, FIZZ3, HXCP1, RSTN

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

11.8 kDa (111aa)

Additionnal Information

Adipose tissue-specific secretory factor, ADSF, C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein A12-alpha-like 2, Cysteine-rich secreted protein FIZZ3, FIZZ3, HXCP1, MGC126603, MGC126609, Resistin, RETN1, RSTN, XCP1, ATGP2510-10 µg, ATGP2510-20 µg, ATGP2510-50 µg, ATGP2510-100 µg, ATGP2510-250 µg, ATGP2510-500 µg, ATGP2510-1 mg, ATGP2510-010, ATGP2510-020, ATGP2510-050, ATGP2510-100, ATGP2510-250, ATGP2510-500, ATGP2510-01M

References & Citations

Steppan C.M., et al. (2001) Nature. 409:307-312; ; Holcomb I.N., et al. (2000) EMBO J. 19:4046-4055

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Metabolism

NCBI Accession Number

NP_065148

Uniprot Accession Number

Q9HD89

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MKTLCSMEEA INERIQEVAG SLIFRAISSI GLECQSVTSR GDLATCPRGF AVTGCTCGSA CGSWDVRAET TCHCQCAGMD WTGARCCRVQ P

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