Recombinant human XRCC2 protein

XRCC2 is a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents. Recombinant human XRCC2 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

X-ray repair cross complementing 2, X-ray repair complementing defective repair in Chinese hamster cells 2, FANCU, RAD51-like

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 80% by SDS-PAGE

Molecular Weight

34.3 kDa (303aa)

Additionnal Information

XRCC2, ADSF, RSTN, XCP1, FIZZ3, MGC126603, MGC126609, ATGP2509-10 µg, ATGP2509-20 µg, ATGP2509-50 µg, ATGP2509-100 µg, ATGP2509-250 µg, ATGP2509-500 µg, ATGP2509-1 mg, ATGP2509-010, ATGP2509-020, ATGP2509-050, ATGP2509-100, ATGP2509-250, ATGP2509-500, ATGP2509-01M

References & Citations

Masson J.Y., et al. (2001) Genes Dev. 15:3296-3307; ; Miller K.A., et al. (2002) J. Biol. Chem. 277:8406-8411

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_005422

Uniprot Accession Number

O43543

Species

Human

AA Sequence

MCSAFHR AESGTELLAR LEGRSSLKEI EPNLFADEDS PVHGDILEFH GPEGTGKTEM LYHLTARCIL PKSEGGLEVE VLFIDTDYHF DMLRLVTILE HRLSQSSEEI IKYCLGRFFL VYCSSSTHLL LTLYSLESMF CSHPSLCLLI LDSLSAFYWI DRVNGGESVN LQESTLRKCS QCLEKLVNDY RLVLFATTQT IMQKASSSSE EPSHASRRLC DVDIDYRPYL CKAWQQLVKH RMFFSKQDDS QSSNQFSLVS RCLKSNSLKK HFFIIGESGV EFC