Recombinant human XRCC2 protein
XRCC2 is a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents. Recombinant human XRCC2 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
X-ray repair cross complementing 2, X-ray repair complementing defective repair in Chinese hamster cells 2, FANCU, RAD51-like
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 80% by SDS-PAGE
Molecular Weight
34.3 kDa (303aa)
Additionnal Information
References & Citations
Masson J.Y., et al. (2001) Genes Dev. 15:3296-3307; ; Miller K.A., et al. (2002) J. Biol. Chem. 277:8406-8411
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_005422
Uniprot Accession Number
O43543
Species
Human
AA Sequence
Frequently Asked Questions
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